Benzocaine Hydrochloride CAS 23239-88-5

01 Overview

Benzocaine HCL works by creating a chemical barrier that halts the build-up of sodium, which accumulates as the nerve endings are stimulated by pain. When sodium builds up, electrical signals also build in the nerve endings. These are eventually transmitted to the brain, which interprets the signals as pain.

02 Details

99% Benzocaine Hydrochloride Local Anesthetic Powder Api Benzocaine HCL CAS 23239-88-5

 

Quick detail

 

Product name Benzocaine HCL
Other name Benzocaine Hydrochloride
CAS register number 23239-88-5
EINECS 202-303-5
Molecular formula C9H11NO2.ClH
Molecular weight 201.65
Assay 98.5%
Appearance White crystalline powder
Package 1kg/aluminium foil bag or as required
Usage can be used as pharmaceutical material

 

 

What is benzocaine HCL?

Benzocaine HCL works by creating a chemical barrier that halts the build-up of sodium, which accumulates as the nerve endings are stimulated by pain. When sodium builds up, electrical signals also build in the nerve endings. These are eventually transmitted to the brain, which interprets the signals as pain.

Benzocaine Hcl is also called amino ethyl benzoate, a colorless or white orthorhombic needle-like crystals or crystalline powder. Benzocaine hydrochloride salt is the hydrochloride salt form of the local anesthetic benzocaine, with the same pharmacological effects of benzocaine and weaker effect of anesthesia than procaine. Local absorption is slow with lasting effect. It cannot be used for anesthesia as a result of not being dissolved in water. It can be used for pain relief and anti-itch.

Benzocaine hydrochloride is usually made into powder or oil paste and used to heal wounds, ulcers, burns, skin abrasions and hemorrhoids.

 

Application

 

  • Otic Pain (earache)
  • Surgical or procedural local anesthesia.
  • Benzocaine is used as a key ingredient in numerous pharmaceuticals:
  • Some glycerol-based ear medications for use in removing excess wax as well as relieving ear conditions such as otitis media and swimmers ear.
  • Some previous diet products such as Ayds.
  • Some condoms designed to prevent premature ejaculation. Benzocaine largely inhibits sensitivity on the penis, and can allow for an erection to be maintained longer (in a continuous act) by delaying ejaculation. Conversely, an erection will also fade faster if stimulus is interrupted.
  • Benzocaine mucoadhesive patches have been used in reducing orthodontic pain.

 

 

COA

 

Items tested Specification Result
Characters A white, crystalline powder or colorless crystals. A white crystal.
Identification Ir should comply with the reference standard spectrum.
Uv should comply with the reference standard spectrum.
An orange-red precipitate is performed.
Ir complies with the reference standard spectrum.
Uv complies with the reference standard spectrum.
An orange-red precipitate is performed.
Melting range 88 ~92 degree 89.8-90.2degree
Loss on drying Not more than 1.0% 0.22%
Readily carbonizable substances The resolution has no more color than matching fluid a. Conform
Residue on ignition Not more than 0.1% 0.02%
Heavy metals Not more than 0.001% Conform
Chloride Conform Conform
Assay (hplc) 98.0%-102.0% 99.96%
Ordinary impurities ≤1% Conform
Reaction Conform Conform

 

 

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