Dutasteride / Avodart CAS 164656-23-9
01 Overview
Dutasteride (Avodart) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Used for benign prostatic hyperplasia; however, it increases the risk of erectile dysfunction and decreased sexual desire.
dutasteride-1
Dutasteride02 Details
Male Steroid Hormone Dutasteride Avodart Finasteride For Treat Prostate Disease / Stop Lose Hair CAS 164656-23-9
Quick detail:
Dutasteride (Avodart ) CAS:164656-23-9
Other name: Avodart
1. CAS register number: 164656-23-9
2. Molecular formula: C27H30F6N2O2
3. Molecular weight: 528.53
4. Assay: 99%
5. Appearance: White crystalline powder
Description:
Product name : Dutasteride
Other name : DUTASTERIDE; Duagen; Avodart
CAS : 164656-23-9
Molecular formula: C27H30F6N2O2
Molecular weight: 528.53
Avodart / Dutasteride Dentist Anesthetic Anodyne 164656-23-9 Duagen / Dutasteride
Melting point: 242°C~250°C
Assay: 99%
MF:C27H30F6N2O2
MW:528.53
Packing: as your require
Appearance: White to pale yellow powder.
Storage: shading, confined preservation.
Applications:
Dutasteride is marketed pharmaceutically as Avodart, Avidart, Avolve, Duagen, Dutas, Dutagen, Duprost. For unknown reasons, early clinical trials for dutasteride were abruptly ceased in 2002, then continued later.
Dutasteride is a 5-alpha-reductase inhibitor, meaning it blocks the action of the 5a-reducatse enzymes, that are responsible for 5a-reducing (converting) testosterone into dihydrotestosterone (DHT) by the addition of a double hydrogen bond.
Dutasteride inhibits both isoforms of 5a-reductase, therefore preventing the conversion of testosterone into dihydrotestosterone. This makes Dutasteride a reasonable treatment for Male Pattern Baldness. Of course, when you convert less Testosterone into Dihydrotestosterone, you increase testosterone levels by default (less conversion).
Dutasteride, at 2.5mgs/day is roughly 1.5x more effective than Finasteride at 5mgs/day, at treating hair loss (both halting it as well as regrowing it). In addition, Dutasteride can be used successfully at that same dose to treat prostate enlargement, and a lesser known effect of Dutasteride (again, at that same dose) use is to treat Acne caused by an overabundance of androgens in the body.
For the steroid using athlete suffering from DHT-related side effects, Dutasteride may be the answer. Hairloss, Acne, and prostate growth can all (potentially) be completely halted with the use of this product. Unfortunately, DHT is not all bad, and you potentially lose some muscle hardness (an amorphous quality if ever there is one), and even some of the other qualities we like from our androgen use.
Also…since this only prevents the 5a-reduction of the androgens subject to that conversion into a dihydro form of them…it will likely do nothing to stop hairloss or other symptoms caused entirely by the use of the androgens in the DHT family.
3. Specification:
| Items | Specitication | Results |
| Description | White or off- white coloured powder | white powder |
| Identification (IR)
|
Should match with working standard | complies |
| Solubility | soluble in dichloromethane, slightly soluble in
ethyl acetate, methanol, acetronile, insoluble in water |
complies |
| Melting point | 246.0~252.0℃ | 247.0~248.0℃ |
| Water by KF | Not more than 0.5% | 0.20% |
| Loss on drying | Not more than 0.5% | 0.12% |
| Residue on ignition | Not more than 0.2% | 0.06% |
| Heavy Metals | Not more than 20ppm | complies |
| Relative substances (HPLC) | ||
| Single maximum impurity | Not more than 0.5% | 0.09% |
| Total impurities | Not more than 1.0% | 0.30% |
| Assay by HPLC
(base on drying ) |
Not less than 98.0% and Not more than 102.0% | 99.8% |
|
Residual solvents |
Dichloromethane ≤600 ppm | complies |
| Ethyl acetate ≤5000 ppm | complies | |
| Pyridine ≤200 ppm | complies | |
| Methanol≤3000 ppm | complies | |
| Toluene ≤890 ppm | complies | |
Company Introduction:
(1) High Quality:Wuhan Wang Lianshang Biotechnology Co., Ltd. is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.
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