Levobupivacaine Hydrochloride CAS 27262-48-2
Effective Anti – Pain Local Anesthetic Drugs Levobupivacaine Hydrochloride CAS 27262-48-2
— Local Anesthetic Drugs Basic Information —
|Product name||Levobupivacaine hydrochloride|
|Other name||2-Piperidinecarboxamide,1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride, (2S)- (9CI); 2-Piperidinecarboxamide|
|Appearance||White Crystalline Powder|
|Product categories||Local Anesthetic Drugs ; Active pharmaceutical ingredients|
— Local Anesthetic Drugs Description —
Levobupivacaine hydrochloride is a sodium channel blocker used as a long-acting local anaesthetic for epidural anesthesia . Levobupivacaine is the isomer of bupivacaine , with efficacy similar to that of bupivacaine with a reduced risk of cardiotoxicity .
Levobupivacaine Hydrochloride is the hydrochloride salt of levobupivacaine , an amide derivative with anesthetic property . Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses , thereby resulting in analgesia and anesthesia . In comparison with racemic bupivacaine , levobupivacaine is associated with less vasodilation and has a longer duration of action .
- Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.
- Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.
- The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.
- Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with fentanyl, morphine or clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.
(1) High Quality:Wuhan Wang Lianshang Biotechnology Co., Ltd. is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.
(2) Favorable Price:Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.
(3) Safe Fast Delivery:After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried
(4) Available Shipment Way:EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc
(5) After-Sale Service:We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.