Bupivacaine Hydrochloride CAS 14252-80-3

01 Overview

Bupivacaine Hydrochloride is indicated for the production of local or regional anesthesia or analgesia for surgery , dental and oral surgery procedures , diagnostic and therapeutic procedures , and for obstetrical procedures.

02 Details

Bupivacaine Hydrochloride Local Anesthetic Bupivacaine Hcl Raw Powder CAS 14252-80-3

 

Quick detail:
English name: Bupivacaine hydrochloride
English Name: 1-Butyl-N- (2, 6-dimethylphenyl) -2-piperidinecarboxamide; 1-Butyl-N- (2, 6-dimethylphenyl) -2-piperidinecarboxamide hydrochloride; Bupivocoine HCl; 1-butyl-N- (2, 6-dimethylphenyl) piperidine-2-carboxamide hydrochloride (1: 1); 1-butyl-N- (2, 6-dimethylphenyl) piperidine-2-carboxamide hydrochloride; Bupivacaine HCl; 2-Piperidinecarboxamide,
1-butyl-N – (2, 6-dimethylphenyl) -, monohydrochloride; 2 ‘, 6’-Pipecoloxylidide, 1-butyl-, hydrochloride (6CI); Marcaina; BUPIVACAINE HYDROCHLORIDE ANHYDROUS
CAS: 14252-80-3
EINECS number: 241-917-8
Molecular formula: C18H31ClN2O2
Molecular Weight: 342.9039
Boiling point: 423.4 ° C at 760 mmHg
Flash Point: 209.9 ° C
Vapor Pressure: 2.24E-07mmHg at 25 ° C
Product use: After local anesthesia for surgery and postoperative analgesia

 

Description:

Bupivacaine Hydrochloride is 2-Piperidinecarboxamide , 1-butyl-N-(2,6-dimethylphenyl)- , monohydrochloride , monohydrate , a white crystalline powder that is freely soluble in 95 percent ethanol , soluble in water , and slightly soluble in chloroform or acetone.

 

  • Bupivacaine Hydrochloride is available in sterile isotonic solutions with and without epinephrine (as bitartrate) 1 : 200 ,000 for injection via local infiltration, peripheral nerve block , and caudal and lumbar epidural blocks . Solutions of Bupivacaine Hydrochloride may be autoclaved if they do not contain epinephrine . Solutions are clear and colorless.
  • Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics . It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino , or piperidine group . They differ in this respect from the procaine-type local anesthetics , which have an ester linkage.

 

 

 

Indications and usage:

 

Bupivacaine Hydrochloride is indicated for the production of local or regional anesthesia or analgesia for surgery , dental and oral surgery procedures , diagnostic and therapeutic procedures , and for obstetrical procedures.

 

 

Product Name bupivacaine hydrochloride
Synonyms 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide; 1-Butyl-N-(2,6-
dimethylphenyl)-2-piperidinecarboxamide hydrochloride; Bupivocoine HCl;
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride (1:1);
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride;
Bupivacaine Hcl; 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-,
monohydrochloride; 2′,6′-Pipecoloxylidide, 1-butyl-, hydrochloride (6CI); Marcaina;
BUPIVACAINE HYDROCHLORIDE ANHYDROUS
Molecular Formula C18H31ClN2O2
Molecular Weight 342.9039
InChI InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)

9-8-
10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H

CAS Registry Number 14252-80-3;18010-40-7
EINECS 241-917-8
Molecular Structure  
Boiling point 423.4°C at 760 mmHg
Flash point 209.9°C
Vapour Pressure 2.24E-07mmHg at 25°C

 

 

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