Diethylstilbestrol CAS 56-53-1;6898-97-1
01 Overview
Diethylstilbestrol (DES, former BAN stilboestrol) is a synthetic nonsteroidal estrogen that was first synthesized in 1938. It is also classified as an endocrine disruptor.
diethylstilbestrol
diethylstilbestrol02 Details
High Purity Raw Steroid Powders Diethylstilbestrol CAS 56-53-1 for Estrogen
Diethylstilbestrol
Product Name: Diethylstilbestrol
Synonyms: LABOTEST-BB LT00233101;DIETHYLSTILBESTEROL;DOMESTROL;GRAFESTROL;ESTROSYN;FONATOL;ALPHA;ALPHA,ALPHA’-DIETHYL-(E)-4,4′-STILBENEDIOL
CAS: 56-53-1
MF: C18H20O2
MW: 268.35
EINECS: 200-278-5
Chemical Properties White Solid
Usage A synthetic, nonsteroidal estrogen. Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.
General Description Odorless tasteless white crystalline powder.
Air & Water Reactions Insoluble in water.
Reactivity Profile Diethylstilbestrol is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides .
Fire Hazard Flash point data for Diethylstilbestrol are not available; however, Diethylstilbestrol is probably combustible.
Diethylstilbestrol Description:
Diethylstilbestrol (DES, former BAN stilboestrol) is a synthetic nonsteroidal estrogen that was first synthesized in 1938. It is also classified as an endocrine disruptor. Human exposure to DES occurred through diverse sources, such as dietary ingestion from supplemented cattle feed and medical treatment for certain conditions, including breast and prostate cancers. From about 1940 to 1971, DES was given to pregnant women in the mistaken belief it would reduce the risk of pregnancy complications and losses.
In 1971, DES was shown to cause a rare vaginal tumor in girls and women who had been exposed to this drug in utero. The United States Food and Drug Administration subsequently withdrew DES from use in pregnant women. Follow-up studies have indicated that DES also has the potential to cause a variety of significant adverse medical complications during the lifetimes of those exposed.The United States National Cancer Institute recommends women born to mothers who took DES undergo special medical exams on a regular basis to screen for complications as a result of the drug. Individuals who were exposed to DES during their mothers’ pregnancies are commonly referred to as “DES daughters” and “DES sons”.
| Test Items |
Specification |
Test Results |
|
Properties |
A white or almost crystal powders |
Almost white crystal powders |
|
Identification |
Positive |
Complies |
|
Acid Basicity |
Neutrality is reacted |
Complies |
|
Content |
≥98% | 99.29% |
|
Melting point |
169～172℃ | 170～172℃ |
|
Related substance |
≤0.5% |
Complies |
|
Loss on drying |
≤0.5% | 0.2% |
| Organic volatile impurities |
Complies |
Complies |
|
Sulphated ash |
≤0.1% | 0.02% |
Related Female Hormone Steroids:
| Estradiol | Estrone | Hydrocortisone |
| Estradiol valerate | Estriol | Hydrocortisone acetate |
| Estradiol benzoate | Nylestriol | Meprednisone |
| Estradiol cypionate | Diethylstilbestrol | Prednisone acetate |
| Estradiol enantate | HEXESTROL | Bentelan |
| Ethynyl estradiol | Progesterone | Betamethasone |
| Algestone acetophenide | Medroxyprogesterone acetate | Clobetasol propionate |
| Ethisterone | Norethindrone | Halobetasol propionate |
| 19-Norethindrone acetate | Mifepristone | Deflazacort |
| Norethisterone Enanthate | Methyldienedione | Tazarotene |
| Ethynodiol diacetate | Eplerenone | Ecdysone |
| Pregnenolone acetate | Levonorgestrel | Desloratadine |
| Lynestrenol | Allylestrenol | Prednisolone phosphate sodium |
| Chlormadinone acetate | Dienogestrel | Fluorometholone Acetate |
| Cyproterone acetate | Drospirenone | Dexamethasone Acetate |
| Megestrol acetate | Pregnenolone | Dexamethasone Sodium Phosphate |
| Melengestrol acetate | Mometasone furoate | Dexamethasone palmitate |
| Betamethasone acetate | Beclomethasone dipropionate | Fluocinolone acetonide |
| Betamethasone Dipropionate | Betamethasone 17-valerate |
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