Exemestane / Aromasin CAS 107868-30-4
Exemestane / Aromasin Cancer Treatment Anti Estrogen Steroids for Cutting / Bulking Cycle CAS 107868-30-4
1. CAS No:107868-30-4
2. Molecular Formula: C20H24O2
3. Assay: 97.0%~103.0%
4. Appearance: White or almost White Crystalline Powder.
5. Usage:Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds available for body builders taking anabolic steroids. Additionally, it also raises testosterone in the body, which is a bonus for bodybuilders during post-cycle-therapy.
Aromasin (Exemestane) is one of those weird compounds that nobody really knows what to do with. It’s a third generation Aromatase Inhibitor (AI) just like Arimidex (Anastrozole) and Femera (Letrozole).
Alias: Aromasin ; Exemestan
CAS NO: 107868-30-4
Appearance: white solid powder.
High Purity Exemestane/Aromasin/Exemestan/CAS No: 107868-30-4
the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.
Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.
In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.
Exemestane blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
Hormones are chemical substances that are produced by glands in the body, which enter the bloodstream and cause effects in other tissues. For example, the hormone testosterone made in the testicles and is responsible for male characteristics such as deepening voice and increased body hair. The use of hormone therapy to treat cancer is based on the observation that receptors for specific hormones that are needed for cell growth are on the surface of some tumor cells. Hormone therapies work by stopping the production of a certain hormone, blocking hormone receptors, or substituting chemically similar agents for the active hormone, which cannot be used by the tumor cell. The different types of hormone therapies are categorized by their function and/or the type of hormone that is affected.
Exemestane is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body’s muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink.
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|Description||: White Crystalline Powder||White Powder|
|Assay(by HPLC)||: 98.0~102.0%||98.64%|
|Melting Point||: 191~195°C||193.5~195.0°C|
|Loss On Drying||: 0.5%max||0.19%|
|Specific Rotation||: +288°~ +298°||+290.2°|
|Residue On Ignition||: 0.1%max||0.03%|
|Related Substances||: Total:1.5%max||<1.3%|
|Residue Solvents||: 0.2%max||0.10%|
|Heavy Metals||: 20PPm max||<10PPm|
|Conclusion||The specification conform with enterprise standard.|
1.Exemestane is a drug used to treat breast cancer.
2.Exemestane is a member of the class of drugs known as aromatase inhibitors.
3.Exemestane is indicated for the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.
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