Flibanserin CAS 167933-07-5
01 Overview
Flibanserin, sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD).
02 Details
Safe Sex Steroid Hormones Flibanserin CAS 167933-07-5 for Women Sexual Enhancement
- Basic Information of Sex Steroid Hormones Flibanserin
| Product name | Flibanserin |
| Other Name | Addyi, Bimt; BIMT17BS; Flibanserin(BIMT17) |
| Original | China |
| CAS | 167933-07-5 |
| Molecular formula | C20H21F3N4O |
| MW | 390.4 |
| Brand name | NJBNSteroid |
| Leading time | within 24 hours upon receipt of payment |
| Delivery | Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS |
| Purity | 98% min. |
| Package | Discreet and Hidden package according to specific requirement |
| Appearance | White Powder |
| Certification | SGS, ISO 9001, KOSHER |
| Payment Terms | Western Union, Money Gram , T/T, Bitcoin |
| Minimum Order Quantity | 5g |
| Price | Negotiable |
| Usage | A kind of drug being studied as a treatment for pre-menopausal women with hypoactive sexual desire disorder (HSDD). |
| Molecular structure |
|
- Whate is Sex Steroid Hormones Flibanserin?
- Flibanserin, sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). The medication increases the number of satisfying sexual events per month by about one half over placebo from a starting point of about two to three.The certainty of the estimate is low.The side effects of dizziness, sleepiness, and nausea occur about three to four times more often.
- Flibanserin is a drug developed to treat hypoactive sexual desire disorder (HSDD) in women. Women with HSDD have a chronic lack of interest in sex that cannot be explained by another medical condition. HSDD is also accompanied by feelings of distress.
- Sometimes, flibanserin is called the “female Viagra,” but that term isn’t quite accurate. Viagra is a drug used to treat erectile dysfunction in men and works by improving blood flow to the penis. In other words, it mainly works on the genitals. Flibanserin is different because it works on a woman’s brain.
- The brain is often considered a woman’s more important sexual organ. Much of her sexual response cycle originates in her brain.
- Technical Test Sheet (TTS) of Sex Steroid Hormones Flibanserin
| Items | Specification |
| Appearance | white crystals or crystalline powder, has a faint, characteristic odor and bitter taste |
| Solubility | freely soluble in water and 95%ethanol, sparingly soluble in acetic anhydride and practically insoluble in diethyl ether |
| pH | 3.5-4.5 |
| Identification
|
1, red to dark purple color appears |
| with(III)iron chloride | |
| 2, light red precipitate formed with reinecke salt TS | |
| 3, UV spectrum meet the reference | |
| 4, solution (1%) responds to the qualitative test for chloride | |
| Melting point | 139-143 celcius degree |
| Clarity and color of solution | clear and colorless |
| Sulfate | 0.048%max |
| Heavy metals | 10ppm max |
| As | 2ppm max |
| Organic acid(0.1M NaOH) | 0.54ml max |
| Loss on drying | 0.5% max |
| Residue on ignition | 0.1%max |
| Residual organic Solvents (GC)
|
Xylol 0.217%max |
| Isopropanol 0.5%max | |
| Related substances(HPLC)
|
Total impurity 1.5%max |
| Single impurity0.5%max | |
| Free P-chloro phenoxy acetic 0.5%max | |
| Count of bacteria
|
bacillus 1000/1g max |
| Mildew 100/1g max | |
| Microzyme 100/1g max | |
| Assay(C12H16CINO3.HCl, on dry basis) | 98%min |
- Clinical Application of Steroid Hormones Flibanserin
Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report a 0.5 increase compared to placebo in the number of times they had “satisfying sexual events”. In those on flibanserin it rose from 2.8 to 4.5 times a month while women receiving placebo reported also an increase of “satisfying sexual events” from 2.7 to 3.7 times a month.The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.
- How Does Sex Steroid Hormones Flibanserin Work?
- Flibanserin works on three important brain chemicals: dopamine, norepinephrine, and serotonin. These chemicals are neurotransmitters. They are responsible for sending signals between the brain and other parts of the body through the nervous system.
- Dopamine and norepinephrine are involved with sexual excitement. However, serotonin contributes to sexual inhibition and may dampen sex drive. It is thought that if these chemicals are out of balance – if dopamine and norepinephrine levels are too low and/or serotonin levels are too high – a woman might feel less sexual desire.
- Flibanserin works by raising levels of dopamine and norepinephrine while lowering levels of serotonin. In this way, chemicals that help promote sexual desire are increased and one that can suppress desire is decreased.
- Flibanserin is a pill to be taken once a day at bedtime.
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