Formestane CAS 566-48-3

01 Overview

Formestane, an aromatase inhibitor, can thus help to decrease the local production of estrogen by blocking the aromatase enzyme in peripheral tissues (ie. adispose tissue of the breast) to treat hormone sensitive breast cancer.

02 Details

Pharmaceutical Intermediates Formestane ( Lentaron ) 566-48-3 for Breast Cancer

 

Quick Detail:

Product Name:Formestane

CAS:566-48-3

MF:C19H26O3

MW:302.41

storage temp. : 2-8°C

form : solid

Formestane Structure

Product Categories: Pharmaceutical Raw Materials; Miscellaneous Biochemicals; Inhibitors;Intermediates&Fine Chemical;Pharmaceuticals; Steroids; Anti-cancer&immunity

 

 

 

Description

 

Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection.
Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor.
Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified.
 

Applications:
Formestane is a drug that has been previously used in breast cancer treatment. Like most drugs which have some sort of phsyique usage, athletes eventually get a hold of it. Formestane is currently one of the best legal anti-estrogens out there. It is classified as an irreversible arromatase inhibitor, meaning, it destroys the aromatase enzyme.

 

Another name for formestane is hydroxyandrostenedione. For those of you who don’t already know, andostenedione is and always was a lousy physique supplement (or drug, whichever you like to call it). As wel all know, the even the prohormones are now illegal in the US (as of Jan 20th, 2005). Tell me how weird chemistry can be…regular androstenedione is highly aromatizable. It converts to estogen very, very readily. When it was legal and everyone was using some form of it, I heard of numerous cases of gyno from it. At the time it was legal and was an over the counter supplement. Imagine getting gyno from something that isn’t even helping you build mass? That sucks.

 

Anyway, all formestane is, is androstenedione with one little hydroxyl (OH) group atttached at the fourth carbon. This small alteration turns a lousy physique androgen which aromatizes highly and has no real true use for us…into one of the best anti-estrogens you can obtain (legal or otherwise). Weird chemistry, huh?

 

Formestane has a very long active life on the order of 24-36 hours. You can get any sport supplement version capsules for around $40 US or less. This amount of $ will usually last you about 3-4 weeks at a sufficient dosage of 200-400mg per day. I have found 200mg a day to be perfect for on cycle anti-estrogen usage and for post-cycle recovery of natural testosterone. Formestane has zero negative feedback (even though it is an androgen by definition) and serves to elevate natural testosterone as well as any anti-estrogen/anti-aromatase drug out there, next to clomid.

 

Specifications:

 

TEST ITEMS                SPECIFICATION RESULTS
Description :    White or Almost White Crystalline Powder white powder
Identification :    A.B. Positive
Assay :    97.0~103.0% 99.3%
Specific Rotation :    +101°~+105° +102.6°
Loss On Drying :    1.0%max 0.27%
Melting Point :    153~157°C 153.0~155.0°C
Organic Volatile Impurities :    meets the requirement. Conforms
Related Substances :    meets the requirement. Conforms
Residual Solvents :    meets the requirement. Conforms
Particle Size :    100% ≤ 20 microns Conforms
Conclusion The specification conform with USP30 standard

 

 

Keywords :

 

Formestane

estrogen steroids powder

Raw steroids powder

Steroid and Hormone;

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids

 

 

Company Introduction:

(1) High Quality:Wuhan Wang Lianshang Biotechnology Co., Ltd. is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.

(2) Favorable Price:Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.

(3) Safe Fast Delivery:After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried

(4) Available Shipment Way:EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc

(5) After-Sale Service:We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.

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