Pregnenolone CAS 145-13-1
01 Overview
Pregnenolone is a chemical that is found in our bodies. It can also be made in a laboratory. People use it for medicine.Pregnenolone is used for fatigue and increasing energy; Alzheimer’s disease and enhancing memory; trauma and injuries; as well as stress and improving immunity.
02 Details
Natural Progesterone Products Pregnenolone CAS 145-13-1 Adrenal Fatigue For Class Medicine Intermediate
1. Basic View :
Product Name: Pregnenolone
CAS: 145-13-1
MF: C21H32O2
MW: 316.48
EINECS: 205-647-4
MP: 188-190 ° C
Alpha: 28.5 º (c=1, EtOH)
Storage temp.: Refrigerator
Merck: 7733
Chemical Properties: White to off-white powder
Usage: Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus.
2 . Product Description :
Pregnenolone is a chemical that is found in our bodies. It can also be made in a laboratory. People use it for medicine.
Pregnenolone is used for fatigue and increasing energy; Alzheimer’s disease and enhancing memory; trauma and injuries; as well as stress and improving immunity.
It is also is used for skin disorders including psoriasis and scleroderma.
Women use pregnenolone for lumpy breasts (fibrocystic breast disease), a disorder of the lining of the uterus (endometriosis), symptoms of menopause, and premenstrual syndrome (PMS).
Some people use pregnenolone for slowing or reversing aging, arthritis, and depression. It is also used for strengthening the heart, allergic reactions, “detoxification,” lupus, multiple sclerosis (MS), prostate problems, and seizures.
3 . Origin about Pregnenolone :
Pregnenolone is a natural hormone that cannot be patented. Back in the 1940’s, when researchers started experimenting with it, they realized that it could be helpful for people under stress and it could increase energy in those who were fatigued. However, about the same time, cortisol, another closely related hormone, was discovered. Cortisol stole the limelight. When cortisol was given to individuals with rheumatoid arthritis, there were outstanding short-term improvements. Photographs of these remarkable recoveries were circulated and the medical community was impressed. Scientists basically put pregnenolone aside to focus on cortisol. The structure of cortisol was altered to make similar molecules such as dexamethasone and prednisone, much more powerful steroids. Dexamethasone and other similar corticosteroids could be patented, and thus a pharmaceutical company could make a lot of money. Pregnenolone has stayed in relative obscurity since the 1940’s, with only rare mentions in the medical literature. There have been few studies published on pregnenolone in recent years, and only a couple involve human subjects.
Applications;
Pregnenolone, like DHEA, is a steroidal hormone manufactured in the body. Pregnenolone is a precursor hormone synthesized from cholesterol, principally in the adrenal glands, but also in the liver, skin, brain, testicles, ovaries, and retina of the eyes.
Steroids are a large family of structurally similar biochemicals that have sex-determining, anti-inflammatory, and growth-regulatory roles. Indeed, pregnenolone is the grand precursor from which almost all of the other steroid hormones are made; including DHEA, progesterone, testosterone, the estrogens, and cortisol. Despite its powerful metabolites, pregnenolone is acknowledged to be without significant side effects, with minimal or no anabolic, estrogenic, or androgenic activity.
Specification;
| Test Items | Specification | Test Results |
| Appearance | White to creamy white crystalline powder | White crystalline powder |
| Identification | IR | Complies |
| Completeness of solution | Meets the requirements.500mg being | Complies |
| dissolved in 10ml of acetone | ||
| Solubility | Insoluble in water, sparingly soluble in | Complies |
| alcohol. Slightly soluble in ether and in | ||
| fixed oils, soluble in acetone; very soluble | ||
| in chloroform. | ||
| Melting range | 213ºC~220ºC | 217ºC |
| Specific optical rotation | +8.8°~ +12.0° | +11.6° |
| Water | ≤0.5% | 0.1% |
| Residue roration | ≤0.2% | 0.06 |
| Heavy metals | ≤0.002% | Complies |
| Assay | 97.0%~103.0% | 99.6% |
| Residual solvents | Methanol≤1000ppm | 74ppm |
| Ethanol≤1000ppm | 39ppm | |
| Methylene chloride≤500ppm | 28ppm | |
| Tetrahydrofuran≤300ppm | ND | |
| Benzene≤2ppm | ND |
Company Introduction:
(1) High Quality:Wuhan Wang Lianshang Biotechnology Co., Ltd. is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.
(2) Favorable Price:Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.
(3) Safe Fast Delivery:After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried
(4) Available Shipment Way:EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc
(5) After-Sale Service:We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.