Sildenafil Mesylate CAS 131543-23-2
01 Overview
Sildenafil Mesylate, same as Sildenafil is an inhibitor of type 5 -cGMP phosphodiesterase relaxing and smoothing muscle cells of the corpus cavernosum which leads to penile erection.
02 Details
Sex Hormones Sildenafil Mesylate Male Enhancement Powders CAS 139755-91-2 Natural Male Sexual Enhancement
Sildenafil Mesylate
CAS: 139755-91-2
Assay: 99% min.
Molecular Formula: C22H30B6O4S. CH3SO3H
Molecular Weight: 570
Packing:foil bags,1kg net/foil bag, 5kg/drum.
Appearance: White or white crystalline powder, odorless, bitter astringent taste, soluble in water and ethanol
Usage: pharmaceutical material, hormone. As a cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) selective inhibitor, penile smooth muscle relaxation allows rapid erection. Sildenafil is cheap, is the development and production of low-cost classes available kidney yang-like the perfect material for medicine and health products.
Standard: USP32
Sildenafil Mesylate Applications:
Sildenafil Mesylate, same as Sildenafil is an inhibitor of type 5 -cGMP phosphodiesterase relaxing and
smoothing muscle cells of the corpus cavernosum which leads to penile erection. This relaxation may be
mediated by nitric oxide via cyclic guanosine monophosphate.
Sildenafil Mesylate Usage:
pharmaceutical material, hormone. As a cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) selective inhibitor, penile smooth muscle relaxation allows rapid erection. Sildenafil is cheap, is the development and production of low-cost classes available kidney yang-like the perfect material for medicine and health products.
Categories: Active Pharmaceutical Ingredients; Miscellaneous Biochemicals; Sildenafil; Erectile Dysfunction.
In 16 separate 4-24 week trials of men (over 18 years old) who suffered from impotence for longer than 6 months, dosages between 10-200 mgs were administered. Significant improvements in erectile function, including frequency of penetration as well as erection duration post penetration, were reported with Sildenfi* treatment compared to the placebo group.
Erections were improved in 72% of group verses 18% of the placebo group. In all cases effects were dependant upon dosage and improvement was the greatest when dosage exceeded 100 mgs. Responses were decreased by 40-60% in patients suffering from diabetes and prostatectomy, respectively. Withdrawal rates were less than 5% related to negative side effects and limited response rates
Hot Sale Raw Steroid Powers Sex Enhancement Sildenafil Mesylate 139755-91-2
Specifications:
| TEST ITEMS | SPECIFICATION | RESULTS |
| Description | White or Almost White Crystalline Powder | white powder |
| Identification | A.B. | Positive |
| Assay | 97.0~103.0% | 99.3% |
| Specific Rotation | +101°~+105° | +102.6° |
| Loss On Drying | 1.0%max | 0.27% |
| Melting Point | 153~157°C | 153.0~155.0°C |
| Organic Volatile Impurities | meets the requirement. | Conforms |
| Related Substances | meets the requirement. | Conforms |
| Residual Solvents | meets the requirement. | Conforms |
| Particle Size | 100% ≤ 20 microns | Conforms |
| Conclusion | The specification conform with USP30 standard | |
COA:
| Test Items | Specification | Test Results |
| Description | White or almost white crystalline powder | White crystalline powder |
| Melting Point | 191.0~193.0°C | 192°C |
| Loss of drying | ≤1.0% | 0.5% |
| Heavy Metal | ≤20ppm | 15ppm |
| TLC | Only one spot | Only one spot |
| Assay | ≥99.5% | 99.91% |
| Conclusion | It complies with the USP 32 | |
Company Introduction:
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