Trimegestone CAS 74513-62-5

01 Overview

Trimegestone (brand name Ondeva), also known as 21-hydroxypromegestone, as well as 17β-((S)-2-hydroxypropanoyl)-17α-methylestra-4,9-dien-3-one, is a steroidal progestin of the 19-norprogesterone group related to promegestone which was introduced in France in 2001 and is used as a hormonal contraceptive and in hormonal replacement therapy for postmenopausal symptoms.

02 Details

New Generation of Progestogen Powder Trimegestone (CAS 74513-62-5)

 

Details:

 

Product Name: Trimegestone
Alias: Trimegestone [INN]; RU 27987; Estra-4,9-dien-3-one, 17- (2-hydroxy-1-oxopropyl) -17-methyl-, (17beta (S)) -; Totelle Sekvens, Ondeva; UNII-4658K0H08W; 17beta- (S) -Lactoyl-17-methylestra-4,9-dien-3-one; (17beta) -17 – [(2S) -2-hydroxypropanoyl] -17-methylestra-4, 9-dien-3-one
CAS: 74513-62-5
Molecular formula: C22H30O3
MW: 342.4718
InChI: InChI = 1 / C22H30O3 / c1-13 (23) 20 (25) 22 (3) 11-9-19-18-6-4-14-12-15 (24) 5-7-16 (14) 17 (18) 8-10-21 (19,22) 2 / h12-13,18-19,23H, 4-11H2,1-3H3 / t13-, 18 +, 19-, 21-, 22 + / m0 / s1
Molecular Structure: 74513-62-5 trimegestone
Density: 1.16g / cm3
Boiling point: 522.6 ° C at 760 mmHg
Flash Point: 284 ° C
Vapor Pressure: 4.16E-13mmHg at 25 ° C

Assay:97%min

Appearance:white or almost white powder.

 

Description:

 

Trimegestone (brand name Ondeva), also known as 21-hydroxypromegestone, as well as 17β-((S)-2-hydroxypropanoyl)-17α-methylestra-4,9-dien-3-one, is a steroidal progestin of the 19-norprogesterone group related to promegestone which was introduced in France in 2001 and is used as a hormonal contraceptive and in hormonal replacement therapy for postmenopausal symptoms. It is not available in the United States.

 

 

 

Applications:

 

Trimegestone has very high affinity for the progesterone receptor, only weak affinity for the mineralocorticoid receptor, and little or no affinity for other steroid hormone receptors.In accordance, it is described as a very potent and pure progestogen,in fact the most potent progestin of the 19-norprogesterone group (clinically effective in endometriosis at only 0.1 mg/day), and possesses weak antimineralocorticoid activity and noandrogenic, antiandrogenic, estrogenic, or glucocorticoid activity.Due to its unique structure, unlike progesterone and some other progestins, trimegestone does not metabolize into neuroactive steroids, and hence does not influence GABAA receptor signaling.

 

 

Company Introduction:

(1) High Quality:Wuhan Wang Lianshang Biotechnology Co., Ltd. is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.

(2) Favorable Price:Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.

(3) Safe Fast Delivery:After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried

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(5) After-Sale Service:We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.

 

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